Archive for the ‘Uncategorized’ Category

Distinguished Professor Charles L. Hussey to Retire

Posted on: December 10th, 2020 by nhammer
Charles L. Hussey, Professor and Fellow of The Electrochemical Society

Charles L. Hussey, Distinguished Professor and Fellow of The Electrochemical Society

 

After 42 years, Dr. Charles L. Hussey, Associate Dean for Research & Graduate Education in the College of Liberal Arts and Distinguished Professor of Chemistry and Biochemistry, is retiring this December.  Hussey first came to the University of Mississippi in 1968 as an undergraduate student majoring in chemistry.  He received the department’s flagship  American Chemical Society (ACS) certified Bachelor of Science in Chemistry in 1971.  He chose to stay at UM and received his PhD in 1974.  After graduation he served on active duty in the USAF at the Frank J. Seiler Research Laboratory at the USAF Academy, where he was also an instructor in the Department of Chemistry. He received the Air Force Commendation Medal for his research work on the development of molten salt-based thermal batteries.  He then returned to the University and has taught courses in analytical chemistry and electrochemistry in the Department of Chemistry and Biochemistry at UM since 1978.  Dr. Hussey served as Chair of the Department of Chemistry and Biochemistry from 1997 until 2017 and then became the first  Associate Dean for Research and Graduate Education in the College of Liberal Arts

Hussey’s research interests are directed at electrochemistry and spectroscopy in molten salts and ionic liquids. His experimental work includes the electro-deposition of metals and alloys, the electrochemistry of lanthanides and actinides as related to the nuclear fuel cycle, the physical and transport properties of molten salts and ionic liquids and the applications of ionic liquids as fluids for chemical engineering processes. He has authored/co-authored more than 160 journal articles and book chapters and is co-inventor on five patents. He co-authored a seminal journal article entitled “Dialkylimidazolium Melts: A New Class of Room Temperature Ionic Liquids for Electrochemistry, Spectroscopy and Synthesis,” which has garnered more than 2,000 citations. Hussey has been the P.I./co-P.I. on more than $8,000,000 in external grants. He has presented papers and given lectures on his work at international conferences and at universities in the U.S. and Europe. In 2014, his research about the electrochemistry of ionic liquids was recognized by the international Max Bredig Award for Molten Salt and Ionic Liquid Chemistry.

For more than 18 years, Dr. Hussey served as a technical editor for the Journal of The Electrochemical Society, the world’s top-ranked journal devoted to the science of electrochemistry. His national service includes the Board of Visitors Review Team for the Battery and Propulsion Directorate at the Wright Laboratory (now AFRL), the National Research Council Committee on Electrometallurgical Techniques for DOE Spent Fuel Treatment, the University of Chicago Review Committee for the Chemical Technology (CMT) Division of Argonne National Laboratory, and the Board of Visitors Review Team for the Chemical Sciences Division of the Army Research Office. He has also served as a consultant to the Lawrence Livermore National Laboratory.

Dr. Hussey was elected Fellow of The Electrochemical Society in 2007 and was designated as an Emeritus Member in 2017. He is a member of Phi Kappa Phi, Sigma Xi, and the Golden Key National Honor Society. In 2014, he received the Southeastern Conference Faculty Achievement Award and the R&D Magazine Top 100 Invention Award. At the University of Mississippi, he has been honored with the Distinguished Research and Creative Achievement Award, the Faculty Achievement Award, and the 25-Year Service Award. In 2018, he was recognized with the Lift Every Voice Award for diversity and inclusion during Black History Month.

Read more about Dr. Hussey in the UM News story.

Chemistry Professors Innovate to Run Labs Safely Amid Pandemic

Posted on: December 3rd, 2020 by nhammer

Chemistry professors and lab coordinators at the University of Mississippi worked with the university’s facilities management and facilities procurement teams to create individual cubicles, made using nonporous barriers, in chemistry labs so students could safely conduct experiments and get in-person instruction during the fall semester.

 

Chemistry professors could lecture about displacement reactions in their sleep, but one displacement problem had them stumped as they planned for fall semester. How could some 1,000 University of Mississippi students, many suddenly uprooted last spring, attend lab sessions during a global pandemic?

When classes started in August, Mississippi’s Department of Health was reporting hundreds of new COVID-19 cases a day.

In response to public health and UM guidelines, Gregory Tschumper, chair and professor of chemistry and biochemistry, and the lab coordinators worked with the university’s facilities management and facilities procurement teams to come up with a proposal for safely distancing students.

Randy Wadkins

 

They decided to create individual cubicles, made using nonporous barriers, in the labs. The department invested in $20,000 of Plexiglas, for which the facilities team coordinated the ordering and installation.

Additional safety measures included students wearing masks and the sanitizing of each station before and after students worked at it. Teaching staff assistants kept common work areas sanitized.

“I hope that our students and other members of the UM family recognize the Herculean effort that has been put forth by chemistry faculty like Dr. John Wiginton, Dr. Safo Aboaku, Dr. Kerri Scott and Dr. Randy Wadkins in our teaching labs this semester,” Tschumper said.

“With all of the safety restrictions imposed by the pandemic, they have gone to extraordinary lengths to convert our laboratory courses to a hybrid format that still regularly includes in-person instruction. It is a privilege to work with such a dedicated group of faculty and teaching assistants.”

To reduce the number of students working in the labs during a given session, the department split the 24-person sessions in half – into an A group and a B group – and rotated the groups so that 12 students at a time could attend face-to-face lab sessions. Those not in the lab watched video experiments produced by graduate students or worked remotely on labs that were available on an online platform.

The new arrangement brought some unanticipated benefits.

Kerri Scott

 

“Initially, I had to be sold on the idea of hybrid labs, said Randy Wadkins, professor of chemistry and biochemistry, “But I soon realized that with smaller numbers I’m getting to know my students better than before.”

Students, too, realized advantages of the rotation concept.

“Rotations allow each student at least two times to perform an experiment each session because there are fewer students,” said Juaneisha Finnie Kennedy, a member of Wadkins’ 400-level biochemistry class from Booneville.

Smaller classes also give professors and instructors more one-on-one time for teaching.

“Faculty and teaching assistants usually can spend seven minutes with a student, but with only 12 per class, we could actually give them twice that amount of time,” said Kerri Scott, instructional professor and associate coordinator of the forensic chemistry program. “The noise level is a lot lower, so it’s easier to have a conversation.”

Safo Aboaku

 

Having 12 students instead of 24 makes lab sessions more relaxed, said Safo Aboaku, an instructional assistant professor of chemistry.

“When you spread students out, the station next to them is empty, so they get a lot more elbow room,” he said. “It’s more comfortable if you have space to maneuver.”

As for increased safety measures such as masking, these students seem to take it in stride.

“Many of us are used to taking extensive measures for safety in labs due to the types of chemicals we can work with, so the additional safety procedures for keeping us safe don’t cause any hindrance to our experience in the labs,” said Guinn Gruber, of Denton, Texas, a student in Scott’s 300-level Quantitative Analysis labs.

“I am certainly grateful that Dr. Scott is taking every precaution to keep a rather vital part of our learning in-person, while also making sure our safety is top priority.”

John Wiginton

 

When safety concerns kept students off-campus campus over the summer, John Wiginton, instructional associate professor and coordinator of undergraduate laboratories, found a feasible solution for the summer students in 100-level General Chemistry labs. These courses, typically taken by first-year students, have the largest enrollment, by far, of any chemistry course.

He partnered with a consortium of lab supply companies to create at-home kits that were custom assembled for Ole Miss general chemistry lab classes and paid for by the department. The kits – beakers, alcohol burners and other equipment, except chemicals – were delivered to the homes of 150 students at no cost to them.

By fall, they were able to take the next level of chemistry, having done at least rudimentary lab work.

“I am very proud of my colleagues in this department, who did the best possible job under really difficult circumstances,” Wadkins said. 

Click here for the original article.

Prof. Gregory Tschumper Named AAAS Fellow!

Posted on: November 27th, 2020 by nhammer
Gregory Tschumper, Chair and Professor of Chemistry & Biochemistry. Photo courtesy of Bella Vie Photography

Gregory Tschumper, Chair and Professor of Chemistry & Biochemistry.

 

Nearly 500 members of the American Association for the Advancement of Science have earned the lifetime distinction of AAAS Fellow.  Professor and Chair Gregory S. Tschumper is now one of them.  He was cited for  contributions in the fields of physical chemistry and computational quantum chemistry, including seminal studies of water clusters, hydrogen bonding and non-covalent interactions. 

AAAS Fellows are elected each year by their peers serving on the Council of AAAS, the organization’s member-run governing body. The title recognizes important contributions to STEM disciplines, including pioneering research, leadership within a given field, teaching and mentoring, fostering collaborations, and advancing public understanding of science.

A virtual induction ceremony for the 489 newly elected Fellows will take place on Feb. 13, 2021, the Saturday following the AAAS Annual Meeting. The honorees will receive official certificates and rosette pins in gold and blue, colors symbolizing science and engineering, by mail.

The tradition of electing AAAS Fellows began in 1874. Since then, the recognition has gone to thousands of distinguished scientists, such as inventor Thomas Edison, elected in 1878, sociologist W. E. B. Du Bois (1905), anthropologist Margaret Mead (1934), computer scientist Grace Hopper (1963), physicist Steven Chu (2000), and astronaut Ellen Ochoa (2012). The 2020 group contains members of each of AAAS’s 24 sections.

AAAS Fellowship often precedes other accolades in long and impactful careers. Two of the 2020 Nobel laureates announced last month, Jennifer Doudna and Charles Rice, are AAAS Fellows. Doudna and a research collaborator received the Nobel Prize in Chemistry for the development of the CRISPR/Cas9 genome editor, while Rice and two colleagues received the Nobel Prize in Physiology or Medicine for contributions to the discovery of the virus that causes Hepatitis C.

In order to be considered for the rank of Fellow, a AAAS member must be nominated by three previously elected Fellows, the steering group of a AAAS section, or the organization’s CEO. Nominations go through a two-step review process, with steering groups reviewing nominations in their section and the AAAS Council voting on the final list.

AAAS leadership has long encouraged its sections and Council to consider diversity when nominating and selecting Fellows, and the association has taken recent steps toward solidifying its commitment to diversity, equity, and inclusion (DEI).

Last month, AAAS published a report that compiles demographic data on the organization’s honorary Fellows, Science and Technology Policy Fellows, award winners, governing bodies, and journal authors and reviewers. The data show that the policy fellows are roughly as diverse as the broader scientific enterprise, while women and racial minorities are underrepresented as elected Fellows. Of note, policy fellows apply to participate in the program, while elected Fellows receive the honor through a nomination process. AAAS has committed to releasing updated data each year to inform its DEI initiatives.

In September 2018, the AAAS Council adopted a revocation policy that allows the organization to rescind honorary Fellowship if warranted. The policy is intended to combat sexual misconduct, racial discrimination, and other breaches of professional ethics and scientific integrity.

An Ionic Forcefield for Nanoparticles

Posted on: November 27th, 2020 by nhammer

Tunable coating allows hitch-hiking nanoparticles to slip past the immune system to their target

Chemistry’s newest assistant professor just had her research published in Science Advances.  She finished this work when she arrived on campus and plans to continue this work at the University of Mississippi.

Nanoparticles are promising drug delivery tools, offering the ability to administer drugs directly to a specific part of the body and avoid the awful side effects so often seen with chemotherapeutics. 

But there’s a problem. Nanoparticles struggle to get past the immune system’s first line of defense: proteins in the blood serum that tag potential invaders. Because of this, only about 1 percent of nanoparticles reach their intended target. 

An SEM image of the nanoparticles on the red blood cell 

 

An SEM image of the nanoparticles on the red blood cell  (Image courtesy of Eden Tanner/ Harvard SEAS)

“No one escapes the wrath of the serum proteins,” said Eden Tanner, a former postdoctoral fellow in bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS). 

Now, Tanner and a team of researchers led by Samir Mitragotri, the Hiller Professor of Bioengineering and Hansjorg Wyss Professor of Biologically Inspired Engineering at SEAS, have developed an ionic forcefield that prevents proteins from binding to and tagging nanoparticles. In mouse experiments, nanoparticles coated with the ionic liquid survived significantly longer in the body than uncoated particles and, surprisingly, 50 percent of the nanoparticles made it to the lungs. It’s the first time that ionic liquids have been used to protect nanoparticles in the blood stream. 

“The fact that this coating allows the nanoparticles to slip past serum proteins and hitch a ride on red blood cells is really quite amazing because once you are able to fight the immune system effectively, lots of opportunities open up,” said Mitragotri, who is also a Core Faculty Member of Harvard’s Wyss Institute for Biologically Inspired Engineering.

The research is published in Science Advances

Ionic liquids, essentially liquid salts, are highly tunable materials that can hold a charge. 

“We knew that serum proteins clear out nanoparticles in the bloodstream by attaching to the surface of the particle and we knew that certain ionic liquids can either stabilize or destabilize proteins,” said Tanner, who is now an Assistant Professor of Chemistry & Biochemistry at the University of Mississippi. “The question was, could we leverage the properties of ionic liquids to allow nanoparticles to slip past proteins unseen.”

“The great thing about ionic liquids is that every small change you make to their chemistry results in a big change in their properties,” said Christine Hamadani, a former graduate student at SEAS and first author of the paper. “By changing one carbon bond, you can change whether or not it attracts or repels proteins.”

Hamadani is currently a graduate student at Tanner’s lab at the University of Mississippi.

SEM image of the ionic liquid coating the nanoparticle

SEM image of the ionic liquid coating the nanoparticle (Image courtesy of Eden Tanner/ Harvard SEAS)

The researchers coated their nanoparticles with the ionic liquid choline hexenoate, which has an aversion to serum proteins. Once in the body, these ionic-liquid coated nanoparticles appeared to spontaneously attach to the surface of red-blood cells and circulate until they reached the dense capillary system of the lungs, where the particles sheared off into the lung tissue. 

“This hitchhiking phenomenon was a really unexpected discovery,” said Mitragotri. “Previous methods of hitchhiking required special treatment for the nanoparticles to attach to red blood cells and even then, they only stayed at a target location for about six hours. Here, we showed 50 percent of the injected dose still in the lungs after 24 hours.” 

The research team still needs to understand the exact mechanism that explains why these particles travel so well to lung tissue, but the research demonstrates just how precise the system can be. 

“This is such a modular technology,” said Tanner, who plans to continue the research in her lab at University of Mississippi. “Any nanoparticle with a surface change can be coated with ionic liquids and there are millions of ionic liquids that can be tuned to have different properties. You could tune the nanoparticle and the liquid to target specific locations in the body.”

“We as a field need as many tools as we can to fight the immune system and get drugs where they need to go,” said Mitragotri. “Ionic liquids are the latest tool on that front.”

The research was co-authored by Morgan J. Goetz. 

https://www.seas.harvard.edu/news/2020/11/ionic-forcefield-nanoparticles

November 25, 2020

Congratulations Chemistry Majors for Inductions into Phi Kappa Phi!

Posted on: November 19th, 2020 by nhammer

UM SMACS Chapter Receives Award for 4th Straight Year!

Posted on: November 2nd, 2020 by nhammer

The University of Mississippi Student Members of the American Chemical Society (SMACS) chapter has been recognized for the 4th straight year by the ACS.  They recently received an Honorable Mention award from the ACS for the 2019-2020 school year. (CLICK HERE)  This adds to the previous awards of Outstanding Chapter (2016-2017), Commendable Chapter (2017-2018), and Honorable Mention (2018-2019).

 

Click here to return to the main Chemistry News page.

 

Two UM Chemistry Professors Take Both Covers in Same JPCA Issue

Posted on: October 26th, 2020 by nhammer
The Journal of Physical Chemistry A (JPCA) publishes two cover articles in each issue. The October 22, 2020 issue is no different. Both covers of the most recent issue are from the Department of Chemistry & Biochemistry at The University of Mississippi – Ole Miss. Greg Tschumper, chair and professor of #chemistry and #biochemistry, and his (former undergraduate) student have the front cover, while Ryan C. Fortenberry, assistant professor of physical chemistry, (along with collaborators) have the supplemental cover. A fascinating coincidence! https://pubs.acs.org/toc/jpcafh/124/42a
 
 
Click here to return to the main Chemistry News page.

Danny Bailey Receives University of Mississippi Staff Service Award!

Posted on: October 9th, 2020 by nhammer
Danny_s

Daniel Bailey, Operations Coordinator for the Department of Chemistry and Biochemistry

Congratulations to Operations Coordinator Danny Bailey for receiving the University of Mississippi Staff Service Award!  Daniel joined the Department of Chemistry and Biochemistry 2014. Danny is originally from Memphis, TN and attended Millsaps College in Jackson, MS where he completed his Business of Administration degree.  Prof Nathan Hammer was quoted as saying, “We are lucky to have Danny.  He is a true asset to the department.”

Click here to return to the main Chemistry News page.

 

 
 

Biochemistry Freshmen Receive Honors College Scholarships

Posted on: October 2nd, 2020 by nhammer

2020 freshman class defined by COVID-19 embodies passion, determination

 

UM freshman receiving scholarships through the Sally McDonnell Barksdale Honors College are: (top, from left) Alexandria Childers, Andie Udziela, Angeline Morgan and Davis Bunn; (second row) Elsi Muños Ramos, Ethan Hebert, Grace Patterson and Jada Kelly; (third row) Jeremy Wright, Kasia Hosey, Molly O’Connor and Porter May; and (bottom) Sarah Caroline Crall, Will Lamb and Yalanis Isabel Wences.

 

OXFORD, Miss. – The Sally McDonnell Barksdale Honors College at the University of Mississippi has awarded more than $500,000 in scholarship money to an incoming freshman class that its leaders said have been more prepared to face adversity in their lifetimes than any other previous class.

This sense of challenge is primarily due to challenges brought on by the global COVID-19 pandemic.

“One thing I saw was a real sense of urgency, amongst our scholarship students especially,” said William Teer, coordinator of enrollment and engagement for the Honors College. “Sometimes people can assume that because you’re 17 or 18 years old, that means you don’t understand real life yet, and I don’t think that’s the case with our student body, especially these scholarship recipients.

“Some have faced significant challenges and overcome significant adversity. Others are very determined to see how they can solve problems they’re passionate about.”

The scholarships range from $6,250 to $8,000 per year over four years as long as the students remain in good standing with the award requirements.

The 2020 freshman receiving scholarships through the Honors College are:

  • Kasia Dione Hosey, a biochemistry major from Laurel, received the McDonnell-Barksdale scholarship.
  • Lorne Turner, an international studies major from Rienzi, received the McDonnell-Barksdale scholarship.
  • Yalanis Isabel Wences, a pharmaceutical sciences major from Forest, received the McDonnell-Barksdale scholarship.
  • Jeremy Wright, a computer science major from Gulfport, received the McDonnell-Barksdale scholarship.
  • Alexandra Nicole Childers, a biological science major from Hurricane, West Virginia, received the Doris Raymond scholarship.
  • Sarah Caroline Crall, an integrated marketing communications major from Palm Beach Gardens, Florida, received the Doris Raymond scholarship.
  • George William Lamb, an international studies major from Memphis, Tennessee, received the Doris Raymond scholarship.
  • Porter Bolton May, an accountancy major from Shreveport, Louisiana, received the Doris Raymond scholarship.
  • Molly Christine O’Connor, an accountancy major from Collierville, Tennessee, received the Doris Raymond scholarship.
  • Jacquelyn Fae Stewart-Kuhn, an international studies major from Mobile, Alabama, received the Doris Raymond scholarship.
  • Davis William Bunn, a public policy leadership major from Birmingham, Alabama, received the Harold Parker Memorial scholarship.
  • Andrea Lee Udziela, a biochemistry major from La Grange, Illinois, received the Harold Parker Memorial scholarship.
  • Ethan Hebert, a pharmaceutical sciences major from Jayess, received the Annexstad Family Foundation Leaders for Tomorrow scholarship.
  • Jada C. Kelly, a pharmaceutical sciences major from Jackson, received the Annexstad Family Foundation Leaders for Tomorrow scholarship.
  • Angeline Marie Morgan, an art major from Southaven, received the Annexstad Family Foundation Leaders for Tomorrow scholarship.
  • Elsi Gabriela Munoz Ramos, an international studies major from Pelahatchie, received the Annexstad Family Foundation Leaders for Tomorrow scholarship.
  • Grace Caroline Patterson, a nursing major from Gulfport, received the Everett-Williams scholarship.

“Looking at these applications, we’re really excited to be able to support the students in fulfilling their dreams,” said John Samonds, Honors College associate dean. “Every year, looking at Honors College applications gives you hope for the future. These are great students, and we’re proud of them.”

The college’s scholarship selection process includes all students who submit the special programs portion of the UM application, with scholarship finalists identified by a selection committee composed of faculty and staff. About 700 students a year are accepted to the Honors College.

“I would say these students’ records demonstrate their ability to adjust to the challenges of the day, and we choose high-performers, students who have a demonstrable resume as both citizen and scholar,” said Douglas Sullivan-González, Honors College dean. “They are more prepared to handle the adversity they are facing than many of us old-timers.”

The college is able to offer such invaluable opportunities to these students thanks to the generous support of the individuals and foundations who fund these scholarships, Sullivan-González said.

Chemical Physics Major Research Featured

Posted on: September 24th, 2020 by nhammer

UM junior Nicholas Kruse, a chemistry and physics major from St. Louis, is a B. S. Chemistry major concentrating in Chemical Physics.

 

OXFORD, Miss. – What’s actually in the electronic cigarettes you’ve been smoking as a “safe” alternative to tobacco?

With much speculation surrounding the safety of e-cigarettes over the past few years, University of Mississippi junior Nicholas Kruse wanted to determine whether top e-cigarette manufacturers are accurately listing ingredients in the e-cigarette fluid that becomes the vapor in “vape.”

“We can’t actually know what the health effects of e-cigarettes are if we don’t know what’s in them,” said Kruse, who is double-majoring in chemistry and physics with minors in German and mathematics.  So, he created a research project to answer that question.

“It’s important for people to understand what they’re putting in their bodies in order for them to make good decisions about their health,” Kruse said.

Step one was identifying the chemical makeup of the brands. Because the information he sought wasn’t always on company websites, Kruse did some research to compile information about e-cigarette fluids.

He then created a research plan that starts with replicating those fluids in lab.

In the next phase of this ongoing study, the compounds will be broken apart into particles, using a laser in a type of chemical analysis called Raman spectroscopy, which is based upon the interaction of light with the chemical bonds within a material.

This cutting-edge instrument analyzes chemical structures in detail, down to the molecular level.  It lets scientists know exactly what is in a chemical compound.

Using these resources, Kruse hopes to identify what is in e-cigarette fluids that isn’t being disclosed by manufacturers.

According to Kruse’s research plan, experiments will be conducted at the Hammer Research Group, founded by his mentor, Nathan I. Hammer, the university’s Margaret McLean Coulter Professor of Chemistry and Biochemistry.

The Hammer Lab is known for cutting-edge research in developing a molecular-level understanding of the effects of noncovalent interactions – the basic chemical bonds found in biological systems – on the properties of new materials and important biological and synthetic building blocks. The lab’s research has been published in leading academic journals, including The Journal of Physical Chemistry.

“I came to the University of Mississippi from my home in St. Louis, Missouri, in order to work in Dr. Hammer’s lab,” Kruse said. “I hope to one day become a research professor at a university, like Dr. Hammer. He’s a pioneer in his field, and I’ve been really lucky to be able to work on his team as an undergraduate.”

For his next project, Kruse will mimic the environment of outer space to study complex chemical compounds. Known as dipole bound-anions, these compounds are found mostly in outer space but also can appear in the human body. Studying them will yield greater insights into multiple scientific disciplines, including pharmacology and the development of drugs.

When he’s not in the lab, Kruse can be found studying German, working on his collection of Star Wars memorabilia or fueling his passion for sharpening Ole Miss students’ academic insights and abilities through tutoring.

“I love teaching,” Kruse said. “There’s nothing like seeing someone’s face light up with joy when they finally understand something.”

Kruse also loves being taught. For his bachelor’s degree in chemistry, he is pursuing a new emphasis in chemical physics offered by the Department of Chemistry and Biochemistry.

Designed for students who enjoy both physics and chemistry, this emphasis is good for students who wish to attend graduate school in physical chemistry or chemical physics

“Nick is a great B.S. chemistry major,” Hammer said. “We are excited that he is doing so well in our program and enjoying research.”

Click Here for the original story.