Vignesh Sundaresan

Vignesh Sundaresan, Assistant Professor of Chemistry and Biochemistry

Assistant Professor of Chemistry & Biochemistry

113 Coulter Hall

EDUCATIONAL AND PROFESSIONAL BACKGROUND

B. Tech., CSIR-Central Electrochemical Research Institute, India, 2014
PhD, Temple University, 2018
Postdoctoral Fellow, University of Notre Dame, 2019-2021

APPOINTMENTS
Assistant Research Professor, University of Notre Dame, 2021-2022
Assistant Professor, University of Mississippi, 2022 – present

RESEARCH INTERESTS
Measurement science at the single-entity level, nanoscale electrochemistry, Optical microscopy and spectroscopy, micro/nanofabrication, and Chemical and biological sensors.

RESEARCH SUMMARY
Imaging electrochemical reactions and biological phenomena at the nanoscale and single entity level can provide rich details on 1) heterogeneity in the system and 2) enhanced mechanistic insights that are not possible with traditional electro- and bio-analytical tools. The Sundaresan Lab vision is to use and develop high-throughput multimodal imaging techniques such as optical, electrochemical, and electron imaging to understand electrochemical and biological phenomena at the single entity level and utilize the obtained insights to design better performing catalytic and biological systems at the ensemble level. Accordingly, the group will focus on interfacing novel high-resolution optical imaging techniques, including super-resolution imaging, with electrochemical techniques that can address fundamental scientific questions in the fields of electrocatalysis, materials science, and biology. Additionally, the developed methodology can be used to design ultra-sensitive chemical and biosensors.

SELECTED PUBLICATIONS
Baek, D. Han, S-R. Kwon, V. Sundaresan and P.W. Bohn. “Electrochemical Zero Mode Waveguide Potential-Dependent Fluorescence of Glutathione Reductase at Single Molecule Occupancy”, Anal. Chem., 2022, 94, 3970-3977

Mannam, Y. Zhang, Y. Zhu, E. Nichols, Q. Wang, V. Sundaresan, S. Zhang, C. Smith, P.W. Bohn, and S.S. Howard. “Real-time Image Denoising of Mixed Poisson-Gaussian Noise in Fluorescence Microscopy Images Using Image J”, Optica, 2022, 9, 335-345